Bacterial Cell Division: Understanding FtsZ Protein Process

Please generate an image illustrating the process of bacterial cell division involving FtsZ protein. Start by showing a bacterial cell replicating its DNA, then show two identical DNA molecules each attached to the cell membrane. Next, depict the division site often located on the DNA region. In the future division site, show the formation of a macromolecular complex called 'divisome', mediating distinct steps during cell division. Illustrate FtsZ polymerizing at the division site into a ring-shaped structure, the Z-ring, which serves as a scaffold for recruiting other division proteins and constricting the cell. Also, present other proteins such as FtsA and ZipA anchoring the Z-ring to the inner cell membrane and FtsK involved in segregating the duplicated DNA. Display FtsI/PBP3, a penicillin-binding protein, building up the peptidoglycan layer specifically at the septum site, forming the peptidoglycan cell wall. As this layer is formed, show the Z-ring contracting and the cell membrane pinching inward, gradually forming a wall-like structure called septum. Progressively illustrate septum separating into two new cells. Lastly, depict a close-up of the three-dimensional structure of FtsZ showing the N-terminal domain with six β-sheets surrounded by α-helices, the C-terminal domain with four parallel arranged β-sheets surrounded by α-helices, the inter-domain cleft, the GTP binding site, and the polymerization interface.